Journal: Bioactive Materials
Article Title: Multifunctional DNA hydrogels with light-triggered gas-therapy and controlled G-Exos release for infected wound healing
doi: 10.1016/j.bioactmat.2025.06.004
Figure Lengend Snippet: Characterization and promoting wound-healing function of G-Exos. (A) Schematic diagram showing the function of exosomes; (B) TEM image and (C) The NTA result of G-Exos; (D) Cell viability of HUVECs and HaCat cells treated with different concentration of G-Exos; The cell proliferation and migration effect of different concentration of G-Exos on (E) HUEVCs and (F) HaCat cells detected by scratch assay; (G) Confocal images of RAW264.7 cells uptaking of G-Exos; (H) The fluorescent images of iNOS and CD206 expression of RAW264.7 cells under different treatments and (I) Semi-quantitative fluorescence of iNOs and CD206 expression of RAW264.7 cells under different treatments; the concentration of (J) IL-6, (K) IL-10, (L) TNF-α secreted by cells after different treatments, data are presented as means ± SD (n = 3), ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001.
Article Snippet: CD86-FITC, anti-mouse CD86 and anti-rabbit CD206 antibodies were purchased from Proteintech Group, Inc (Wuhan, China).
Techniques: Concentration Assay, Migration, Wound Healing Assay, Expressing, Fluorescence